USP22 anticorps (Middle Region)
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- Antigène Voir toutes USP22 Anticorps
- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp USP22 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PSSCLVCEMS SLFQEFYSGH RSPHIPYKLL HLVWTHARHL AGYEQQDAHE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against USP22. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human USP22
- Top Product
- Discover our top product USP22 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 525 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
- Autre désignation
- USP22 (USP22 Produits)
- Synonymes
- anticorps USP3L, anticorps AI427806, anticorps zgc:136342, anticorps usp22, anticorps usp22 b, anticorps usp22-B, anticorps usp22-a, anticorps usp3l, anticorps ubiquitin specific peptidase 22, anticorps ubiquitin specific peptidase 22 S homeolog, anticorps USP22, anticorps Usp22, anticorps usp22, anticorps usp22.S
- Sujet
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USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
Alias Symbols: KIAA1063, USP3L
Protein Interaction Partner: UBC, AASDHPPT, STAT3, TAF10, TADA2A, ATXN7, MYC, KAT2A, TRRAP, TAF9B, HIST1H2BD, TADA3, SUMO1, NFATC2, SIRT1, ATXN7L3, FUBP1, HIST2H2BE, HIST2H2AC, MRPL44, ATXN7L3B, USP27X, KIF7, KLHL23, ATXN7L2, TADA1, CCDC101, TADA2B, ENY2, SUPT20H, TAF5L, SND1, CNOT10
Protein Size: 525 - Poids moléculaire
- 60 kDa
- ID gène
- 23326
- NCBI Accession
- NM_015276, NP_056091
- UniProt
- Q9UPT9
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