USP22 anticorps (Middle Region)
Aperçu rapide pour USP22 anticorps (Middle Region) (ABIN2787647)
Antigène
Voir toutes USP22 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- USP22 Antibody - middle region
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Séquence
- PSSCLVCEMS SLFQEFYSGH RSPHIPYKLL HLVWTHARHL AGYEQQDAHE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against USP22. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human USP22
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58353-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
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Autre désignation
- USP22
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Sujet
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Background Information: USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
Gene Name: Ubiquitin specific peptidase 22
Alternative Symbols: USP3L
Protein Name: Ubiquitin carboxyl-terminal hydrolase 22
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Poids moléculaire
- 60kDa
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ID gène
- 23326
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NCBI Accession
- NP_056091
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UniProt
- Q9UPT9
Antigène
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