CBX2 anticorps (Middle Region)
Aperçu rapide pour CBX2 anticorps (Middle Region) (ABIN2787656)
Antigène
Voir toutes CBX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- CBX2 Antibody - middle region
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Séquence
- SDSDPDSASP PSTGQNPSVS VQTSQDWKPT RSLIEHVFVT DVTANLITVT
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Homologie
- Cow: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against CBX2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CBX2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58370-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CBX2 (Chromobox Homolog 2 (CBX2))
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Autre désignation
- CBX2
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Sujet
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Background Information: CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Gene Name: Chromobox homolog 2
Alternative Symbols: M33, CDCA6, SRXY5
Protein Name: Chromobox protein homolog 2
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Poids moléculaire
- 56kDa
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ID gène
- 84733
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NCBI Accession
- NP_005180
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UniProt
- Q14781
Antigène
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