APRT anticorps (N-Term)

N° du produit ABIN2787672

Cet anticorps anti-APRT Polyclonal Lapin (ABIN2787672) détecte spécifiquement APRT dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Chien, Boeuf (Vache) et Cobaye.

Aperçu rapide pour APRT anticorps (N-Term) (ABIN2787672)

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Reactivité: Humain, Rat, Chien, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APRT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-APRT anticorps

Épitope: N-Term

Fonction: APRT Antibody - N-terminal region

Séquence: ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human APRT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58422-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur APRT

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Autre désignation: APRT

Sujet:

Background Information: Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Adenine phosphoribosyltransferase

Alternative Symbols: AMP, APRTD

Protein Name: Adenine phosphoribosyltransferase

Poids moléculaire: 20kDa

ID gène: 353

NCBI Accession: NP_000476

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process