Dynamitin anticorps (N-Term)

N° du produit ABIN2787686

L’anticorps anti-Dynamitin Polyclonal Lapin est utilisé pour la détection de Dynamitin dans des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour Dynamitin anticorps (N-Term) (ABIN2787686)

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamitin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Dynamitin anticorps

Épitope: N-Term

Fonction: DCTN2 Antibody - N-terminal region

Séquence: ADPKYADLPG IARNEPDVYE TSDLPEDDQA EFDAFAQELE ELTSTSVEHI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DCTN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DCTN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58450-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Dynamitin

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Autre désignation: DCTN2

Sujet:

Targeted Subunit: 2

Background Information: DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Dynactin 2 (p50)

Alternative Symbols: RBP50, DCTN50, HEL-S-77, DYNAMITIN

Protein Name: Dynactin subunit 2

Poids moléculaire: 45kDa

ID gène: 10540

NCBI Accession: NP_006391

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization