Dynamitin anticorps (N-Term)

N° du produit ABIN2787686

Détail du produit anti-Dynamitin anticorps

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamitin est non-conjugé

Application: Western Blotting (WB)

Séquence: ADPKYADLPG IARNEPDVYE TSDLPEDDQA EFDAFAQELE ELTSTSVEHI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DCTN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DCTN2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 406 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Dynamitin

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Autre désignation: DCTN2 (DCTN2 Produits)

Synonymes: anticorps DCTN2, anticorps dctn2, anticorps dctn50, anticorps dynamitin, anticorps rbp50, anticorps CG8269, anticorps DMN, anticorps Dmel\\CG8269, anticorps P50, anticorps dDyn, anticorps dmn, anticorps dyna, anticorps l(2)k16109, anticorps l(2)k16218, anticorps p50, anticorps p50/Dmn, anticorps p50/dynamitin, anticorps 2310042E05Rik, anticorps C130077D06Rik, anticorps C87049, anticorps DCTN-50, anticorps GMP23-48K, anticorps RBP50, anticorps DCTN50, anticorps DYNAMITIN, anticorps zgc:63867, anticorps dynactin subunit 2, anticorps dynactin subunit 2 S homeolog, anticorps Dynactin 2, p50 subunit, anticorps dynactin 2, anticorps dynactin 2 (p50), anticorps dynactin subunit 2 L homeolog, anticorps DCTN2, anticorps dctn2.S, anticorps DCTN2-p50, anticorps dctn2, anticorps Dctn2, anticorps dctn2.L

Sujet: DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DCTN50, DYNAMITIN, RBP50
Protein Interaction Partner: KIFC3, CCDC172, HAUS1, BLOC1S6, DCTN2, BICD2, DYNC1I1, DCTN1, UBC, FLNB, NUP43, LEO1, SEH1L, ACTR10, DCTN4, DCTN3, ACTR1A, ACTR1B, RABEP1, LMNB1, GADD45A, KPNA2, SMURF1, DYNLRB1, STRN4, RANBP9, TPM4, SNRPA1, PSMD4, PSMD1, PSMC4, PSMC2, POLR2D, POLR2A, MCM
Protein Size: 406

Poids moléculaire: 45 kDa

ID gène: 10540

NCBI Accession: NM_006400, NP_006391

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization