DLD anticorps (Middle Region)

N° du produit ABIN2787688

Cet anticorps anti-DLD est un anticorps Lapin Polyclonal détectant DLD dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio). Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour DLD anticorps (Middle Region) (ABIN2787688)

Antigène: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DLD anticorps

Épitope: Middle Region

Séquence: AGEMVNEAAL ALEYGASCED IARVCHAHPT LSEAFREANL AASFGKSINF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 86%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DLD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DLD

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 509 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DLD (ABIN2787688)

Ayanniyi, Raji, Adegoke: "Prevalence of asymptomatic sacroiliac joint dysfunction and its association with leg length discrepancies in male students in selected junior secondary schools in Ibadan." dans: African journal of medicine and medical sciences, Vol. 37, Issue 1, pp. 37-42, (2008) (PubMed).

Détails sur DLD

Antigène: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Autre désignation: DLD

Sujet: DLD is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DLDH, E3, GCSL, LAD, PHE3
Protein Interaction Partner: HUWE1, FUS, UBC, SUMO1, NEDD8, MDM2, ASB15, PEPD, LDHA, CKB, ASS1, CNDP2, TNFAIP8, DPP3, RPL23, FN1, ATF2, MRPL11, UBAP2, MRPL37, MRPL13, MRPL42, GGH, UQCRC2, UQCRC1, MRPL23, NONO, NDUFB5, NDUFA9, ETFB, DLAT, DBT, AK2, SIRT7, SLC2A4, PSMD4, OGDH, DLD, PDH
Protein Size: 509

Poids moléculaire: 56 kDa

ID gène: 1738

NCBI Accession: NM_000108, NP_000099

UniProt: B2R5X0

Pathways: Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis