GPX4 anticorps (Middle Region)

N° du produit ABIN2787700

Cet anticorps anti-GPX4 Polyclonal Lapin (ABIN2787700) détecte spécifiquement GPX4 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cobaye, Boeuf (Vache), Chévre et Saccharomyces cerevisiae.

Aperçu rapide pour GPX4 anticorps (Middle Region) (ABIN2787700)

Antigène: GPX4 (Glutathione Peroxidase 4 (GPX4))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cobaye, Boeuf (Vache), Chévre, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPX4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GPX4 anticorps

Épitope: Middle Region

Fonction: GPX4 Antibody - middle region

Séquence: QUGKTEVNYT QLVDLHARYA ECGLRILAFP CNQFGKQEPG SNEEIKEFAA

Homologie: Cow: 86%, Goat: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rat: 86%, Yeast: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GPX4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GPX4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58473-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPX4

Antigène: GPX4 (Glutathione Peroxidase 4 (GPX4))

Autre désignation: GPX4

Sujet:

Background Information: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

Gene Name: Glutathione peroxidase 4

Alternative Symbols: MCSP, SMDS, GPx-4, PHGPx, snGPx, GSHPx-4, snPHGPx

Protein Name: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial

Poids moléculaire: 19 kDa

ID gène: 2879

NCBI Accession: NP_002076

UniProt: P36969