PNPO anticorps (N-Term)

N° du produit ABIN2787718

Cet anticorps anti-PNPO est un anticorps Lapin Polyclonal détectant PNPO dans WB. Adapté pour Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye et Lapin. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour PNPO anticorps (N-Term) (ABIN2787718)

Antigène: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNPO est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PNPO anticorps

Épitope: N-Term

Séquence: PMRKSYRGDR EAFEETHLTS LDPVKQFAAW FEEAVQCPDI GEANAMCLAT

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNPO. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PNPO

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 261 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PNPO (ABIN2787718)

Song, Ueno, Numata, Iga, Shibuya-Tayoshi, Nakataki, Tayoshi, Yamauchi, Sumitani, Tomotake, Tada, Tanahashi, Itakura, Ohmori: "Association between PNPO and schizophrenia in the Japanese population." dans: Schizophrenia research, Vol. 97, Issue 1-3, pp. 264-70, (2007) (PubMed).

Détails sur PNPO

Antigène: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Autre désignation: PNPO

Sujet: PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO, EC 1.4.3.5).[supplied by OMIM].
Alias Symbols: FLJ10535, PDXPO
Protein Interaction Partner: UBC, LPP, APP, ELAVL1,
Protein Size: 261

Poids moléculaire: 29 kDa

ID gène: 55163

NCBI Accession: NM_018129, NP_060599

UniProt: Q9NVS9