PNPO anticorps (N-Term)

N° du produit ABIN2787718

Cité dans 1 publication. Cet anticorps anti-PNPO Polyclonal Lapin (ABIN2787718) détecte spécifiquement PNPO dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye et Lapin.

Aperçu rapide pour PNPO anticorps (N-Term) (ABIN2787718)

Antigène: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNPO est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PNPO anticorps

Épitope: N-Term

Fonction: PNPO Antibody - N-terminal region

Séquence: PMRKSYRGDR EAFEETHLTS LDPVKQFAAW FEEAVQCPDI GEANAMCLAT

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNPO. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PNPO

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58515-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PNPO (ABIN2787718)

Song, Ueno, Numata, Iga, Shibuya-Tayoshi, Nakataki, Tayoshi, Yamauchi, Sumitani, Tomotake, Tada, Tanahashi, Itakura, Ohmori: "Association between PNPO and schizophrenia in the Japanese population." dans: Schizophrenia research, Vol. 97, Issue 1-3, pp. 264-70, (2007) (PubMed).

Détails sur PNPO

Antigène: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Autre désignation: PNPO

Sujet:

Background Information: PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO, EC 1.4.3.5).[supplied by OMIM].

Gene Name: Pyridoxamine 5'-phosphate oxidase

Alternative Symbols: PDXPO, HEL-S-302

Protein Name: Pyridoxine-5'-phosphate oxidase

Poids moléculaire: 29kDa

ID gène: 55163

NCBI Accession: NP_060599

UniProt: Q9NVS9