BPNT1 anticorps (N-Term)

N° du produit ABIN2787757

Cet anticorps anti-BPNT1 est un anticorps Lapin Polyclonal détectant BPNT1 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval et Porc.

Aperçu rapide pour BPNT1 anticorps (N-Term) (ABIN2787757)

Antigène: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPNT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BPNT1 anticorps

Épitope: N-Term

Séquence: DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 261 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BPNT1

Antigène: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Autre désignation: BPNT1

Sujet: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Alias Symbols: PIP
Protein Interaction Partner: SUMO2, UBC, IQCB1,
Protein Size: 261

Poids moléculaire: 29 kDa

ID gène: 10380

NCBI Accession: NM_006085, NP_006076

UniProt: O95861

Pathways: Inositol Metabolic Process