BPNT1 anticorps (N-Term)

N° du produit ABIN2787757

Cet anticorps anti-BPNT1 Polyclonal Lapin (ABIN2787757) détecte spécifiquement BPNT1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval et Porc.

Aperçu rapide pour BPNT1 anticorps (N-Term) (ABIN2787757)

Antigène: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPNT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BPNT1 anticorps

Épitope: N-Term

Fonction: BPNT1 Antibody - N-terminal region

Séquence: DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58597-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BPNT1

Antigène: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Autre désignation: BPNT1

Sujet:

Background Information: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Gene Name: 3'(2'), 5'-bisphosphate nucleotidase 1

Alternative Symbols: PIP, HEL20

Protein Name: 3'(2'),5'-bisphosphate nucleotidase 1

Poids moléculaire: 29kDa

ID gène: 10380

NCBI Accession: NP_006076

UniProt: O95861

Pathways: Inositol Metabolic Process