CAPZA3 anticorps (N-Term)

N° du produit ABIN2787761

L’anticorps anti-CAPZA3 Polyclonal Lapin est utilisé pour la détection de CAPZA3 dans des échantillons de Humain, Souris, Rat, Chien, Cobaye et Lapin. Il a été validé pour WB.

Aperçu rapide pour CAPZA3 anticorps (N-Term) (ABIN2787761)

Antigène: CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAPZA3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CAPZA3 anticorps

Épitope: N-Term

Fonction: CAPZA3 Antibody - N-terminal region

Séquence: MTLSVLSRKD KERVIRRLLL QAPPGEFVNA FDDLCLLIRD EKLMHHQGEC

Homologie: Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CAPZA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPZA3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58604-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CAPZA3

Antigène: CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))

Autre désignation: CAPZA3

Sujet:

Targeted Subunit: alpha-3

Background Information: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.

Gene Name: Capping protein (actin filament) muscle Z-line, alpha 3

Alternative Symbols: Gsg3, CAPPA3, HEL-S-86

Protein Name: F-actin-capping protein subunit alpha-3

Poids moléculaire: 33kDa

ID gène: 93661

NCBI Accession: NP_201585

UniProt: Q96KX2

Pathways: Regulation of Actin Filament Polymerization