FN3KRP anticorps (N-Term)

N° du produit ABIN2787771

Cité dans 1 publication. Cet anticorps anti-FN3KRP Polyclonal Lapin (ABIN2787771) détecte spécifiquement FN3KRP dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Chien, Cobaye et Cheval.

Aperçu rapide pour FN3KRP anticorps (N-Term) (ABIN2787771)

Antigène: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FN3KRP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FN3KRP anticorps

Épitope: N-Term

Fonction: FN3KRP Antibody - N-terminal region

Séquence: MDPGDPAGDP AAGERHRMGR DPLLLLQALQ TLWSTRERKQ LREEAWRGFA

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FN3KRP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FN3KRP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58624-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FN3KRP (ABIN2787771)

Szwergold, Manevich, Payne, Loomes: "Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme." dans: Biochemical and biophysical research communications, Vol. 361, Issue 4, pp. 870-5, (2007) (PubMed).

Détails sur FN3KRP

Antigène: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Autre désignation: FN3KRP

Sujet:

Background Information: FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM].

Gene Name: Fructosamine 3 kinase related protein

Alternative Symbols: FN3KL

Protein Name: Ketosamine-3-kinase

Poids moléculaire: 34kDa

ID gène: 79672

NCBI Accession: NP_078895

UniProt: Q9HA64