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alpha KGDHC anticorps (N-Term)

alphaKGDHC Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787780
  • Antigène Voir toutes alpha KGDHC (alphaKGDHC) Anticorps
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    Épitope
    • 8
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Lapin
    Hôte
    • 36
    • 1
    Lapin
    Clonalité
    • 36
    • 1
    Polyclonal
    Conjugué
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp alpha KGDHC est non-conjugé
    Application
    • 26
    • 20
    • 19
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL
    Homologie
    Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against OGDH. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human OGDH
    Top Product
    Discover our top product alphaKGDHC Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 427 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    Autre désignation
    OGDH (alphaKGDHC Produits)
    Synonymes
    anticorps AKGDH, anticorps E1k, anticorps OGDC, anticorps 2210403E04Rik, anticorps 2210412K19Rik, anticorps AA409584, anticorps d1401, anticorps mKIAA4192, anticorps oxoglutarate dehydrogenase, anticorps oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide), anticorps OGDH, anticorps Ogdh
    Sujet
    The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
    Alias Symbols: AKGDH, E1k, OGDC
    Protein Interaction Partner: MDM2, UBC, SUMO1, NEDD8, CPSF7, MRPL38, MRPL41, TSR1, MRPS2, MRPL15, MRPL13, SCFD1, PDHX, SSBP1, SUMO2, PDHB, PDHA1, DLST, DLAT, DHODH, ISG15, USP13, PLSCR1, DLD,
    Protein Size: 427
    Poids moléculaire
    47 kDa
    ID gène
    4967
    NCBI Accession
    NM_001003941, NP_001003941
    UniProt
    Q96DD3
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