TMED10 anticorps (Middle Region)

N° du produit ABIN2787806

Détail du produit anti-TMED10 anticorps

Antigène: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMED10 est non-conjugé

Application: Western Blotting (WB)

Séquence: KLKPLEVELR RLEDLSESIV NDFAYMKKRE EEMRDTNEST NTRVLYFSIF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TMED10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TMED10

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 219 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TMED10

Antigène: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Autre désignation: TMED10 (TMED10 Produits)

Synonymes: anticorps tmp21, anticorps P24(DELTA), anticorps S31I125, anticorps S31III125, anticorps TMP21, anticorps Tmp-21-I, anticorps p23, anticorps 1110014C03Rik, anticorps Tmp21, anticorps p24delta1, anticorps fe06g04, anticorps wu:fb98e10, anticorps wu:fe06g04, anticorps zgc:85681, anticorps transmembrane p24 trafficking protein 10 L homeolog, anticorps transmembrane p24 trafficking protein 10, anticorps tmed10.L, anticorps TMED10, anticorps Tmed10, anticorps tmed10

Sujet: TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23
Protein Interaction Partner: UBC, SUMO1, NEDD8, ASB8, RNF2, FBXO6, rev, TMED9, COPZ1, SEC23B, UBL4A, DHODH, ATF2, VCP, PTRF, S100A16, NIT2, PRDX6, SEC22B, EIF3C, VAMP2, COPG1, COPE, COPB2, COPB1, COPA, ARCN1, CDK2, EBNA-LP, RYK, TMED2, PSENEN, APH1A, NCSTN, ARF1, GORASP2,
Protein Size: 219

Poids moléculaire: 24 kDa

ID gène: 10972

NCBI Accession: NM_006827, NP_006818

UniProt: P49755