TMED10 anticorps (Middle Region)
Aperçu rapide pour TMED10 anticorps (Middle Region) (ABIN2787806)
Antigène
Voir toutes TMED10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- TMED10 Antibody - middle region
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Séquence
- KLKPLEVELR RLEDLSESIV NDFAYMKKRE EEMRDTNEST NTRVLYFSIF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against TMED10. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TMED10
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58728-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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Autre désignation
- TMED10
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Sujet
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Background Information: TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Gene Name: Transmembrane emp24-like trafficking protein 10 (yeast)
Alternative Symbols: p23, TMP21, p24d1, S31I125, Tmp-21-I, S31III125, P24(DELTA)
Protein Name: Transmembrane emp24 domain-containing protein 10
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Poids moléculaire
- 24kDa
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ID gène
- 10972
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NCBI Accession
- NP_006818
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UniProt
- P49755
Antigène
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