GARS anticorps (Middle Region)

N° du produit ABIN2787816

Cet anticorps Lapin Polyclonal détecte spécifiquement GARS dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Boeuf (Vache).

Aperçu rapide pour GARS anticorps (Middle Region) (ABIN2787816)

Antigène: GARS (Glycyl-tRNA Synthetase (GARS))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GARS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GARS anticorps

Épitope: Middle Region

Fonction: GARS Antibody - middle region

Séquence: IEPSFGLGRI MYTVFEHTFH VREGDEQRTF FSFPAVVAPF KCSVLPLSQN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GARS

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58758-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GARS

Antigène: GARS (Glycyl-tRNA Synthetase (GARS))

Autre désignation: GARS

Sujet:

Background Information: GARS catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Glycyl-tRNA synthetase

Alternative Symbols: GARS, HMN5, CMT2D, DSMAV, GlyRS, HMN5A, SMAD1, SMAJI

Protein Name: Glycine--tRNA ligase

Poids moléculaire: 83kDa

ID gène: 2617

NCBI Accession: NP_002038

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process