GARS anticorps (Middle Region)

N° du produit ABIN2787816

Détail du produit anti-GARS anticorps

Antigène: GARS (Glycyl-tRNA Synthetase (GARS))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GARS est non-conjugé

Application: Western Blotting (WB)

Séquence: IEPSFGLGRI MYTVFEHTFH VREGDEQRTF FSFPAVVAPF KCSVLPLSQN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GARS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 739 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GARS

Antigène: GARS (Glycyl-tRNA Synthetase (GARS))

Autre désignation: GARS (GARS Produits)

Synonymes: anticorps CMT2D, anticorps DSMAV, anticorps GlyRS, anticorps HMN5, anticorps SMAD1, anticorps Aat-gly, anticorps CG6778, anticorps Dmel\\CG6778, anticorps GRS, anticorps gars, anticorps team, anticorps RGD1559871, anticorps GENA202, anticorps Gena201, anticorps Nmf249, anticorps Sgrp23, anticorps GB13467, anticorps MGC79495, anticorps fb02f03, anticorps si:dkey-276i5.1, anticorps wu:fb02f03, anticorps NI36_08435, anticorps glycyl-tRNA synthetase, anticorps Glycyl-tRNA synthetase, anticorps glycine--tRNA ligase, anticorps glycyl-tRNA synthetase L homeolog, anticorps Glycine--tRNA ligase, anticorps GARS, anticorps GlyRS, anticorps Gars, anticorps LOC408392, anticorps gars.L, anticorps gars, anticorps LOC692991, anticorps glyQ, anticorps TTHA0543, anticorps NI36_RS08405

Sujet: GARS catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Protein Interaction Partner: UBC, STAU1, NEDD8, DCP2, TNRC6B, CAND1, GORASP2, CORO1C, BOP1, GANAB, XPO7, HSPA4L, VAT1, SEC23A, TOM1, KHSRP, HIRIP3, HIST1H4A, USP11, ZYX, UGDH, TTC1, TROVE2, SNX1, SHMT1, PPM1G, OSBP, NCBP1, ME1, GTF2A1, GFPT1, CTTN, CTNNA1, CARS, APEH, MAPK8, MAP3K10,
Protein Size: 739

Poids moléculaire: 83 kDa

ID gène: 2617

NCBI Accession: NM_002047, NP_002038

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process