ATG4C anticorps (Middle Region)
Aperçu rapide pour ATG4C anticorps (Middle Region) (ABIN2787855)
Antigène
Voir toutes ATG4C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- TISLKETIGK YSDDHEMRNE VYHRKIISWF GDSPLALFGL HQLIEYGKKS
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Homologie
- Cow: 75%, Dog: 91%, Horse: 86%, Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ATG4C. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ATG4C
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 458 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
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Autre désignation
- ATG4C
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Sujet
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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Alias Symbols: APG4-C, APG4C, AUTL1, AUTL3, FLJ14867
Protein Interaction Partner: UBC, SPTLC1, SMC1A, USP11, PSMD2, PSMC5, PSMC4, PSMC2, PSMC1, PRKDC,
Protein Size: 458 -
Poids moléculaire
- 52 kDa
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ID gène
- 84938
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NCBI Accession
- NM_178221, NP_835739
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UniProt
- Q96DT6
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Pathways
- Autophagy
Antigène
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