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Selectin E/CD62e anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement Selectin E/CD62e dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye et Mouton.
N° du produit ABIN2787940

Aperçu rapide pour Selectin E/CD62e anticorps (N-Term) (ABIN2787940)

Antigène

Voir toutes Selectin E/CD62e (SELE) Anticorps
Selectin E/CD62e (SELE) (Selectin E (SELE))

Reactivité

  • 81
  • 25
  • 23
  • 11
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye, Mouton

Hôte

  • 58
  • 49
  • 16
  • 3
  • 1
Lapin

Clonalité

  • 64
  • 63
Polyclonal

Conjugué

  • 76
  • 15
  • 12
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Cet anticorp Selectin E/CD62e est non-conjugé

Application

  • 71
  • 48
  • 42
  • 41
  • 33
  • 28
  • 21
  • 14
  • 11
  • 7
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK DVGMWNDERC

    Homologie

    Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against SELE. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human SELE
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 610 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    Selectin E/CD62e (SELE) (Selectin E (SELE))

    Autre désignation

    SELE

    Sujet

    The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
    Alias Symbols: CD62E, ELAM, ELAM1, ESEL, LECAM2
    Protein Interaction Partner: LGALS3BP, SELL, SERPING1, PXN, PTK2, GLG1, SELPLG, FLNA, VCL, PTPN11, PLCG1, CD44, ACTN2, TLN1,
    Protein Size: 610

    Poids moléculaire

    64 kDa

    ID gène

    6401

    NCBI Accession

    NM_000450, NP_000441

    UniProt

    P16581

    Pathways

    Thromboxane A2 Receptor Signaling
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