Selectin E/CD62e anticorps (N-Term)
Aperçu rapide pour Selectin E/CD62e anticorps (N-Term) (ABIN2787940)
Antigène
Voir toutes Selectin E/CD62e (SELE) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK DVGMWNDERC
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Homologie
- Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against SELE. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SELE
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 610 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Selectin E/CD62e (SELE) (Selectin E (SELE))
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Autre désignation
- SELE
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Sujet
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The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Alias Symbols: CD62E, ELAM, ELAM1, ESEL, LECAM2
Protein Interaction Partner: LGALS3BP, SELL, SERPING1, PXN, PTK2, GLG1, SELPLG, FLNA, VCL, PTPN11, PLCG1, CD44, ACTN2, TLN1,
Protein Size: 610 -
Poids moléculaire
- 64 kDa
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ID gène
- 6401
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NCBI Accession
- NM_000450, NP_000441
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UniProt
- P16581
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Pathways
- Thromboxane A2 Receptor Signaling
Antigène
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