Selectin E/CD62e anticorps (N-Term)

N° du produit ABIN2787940

Cet anticorps Lapin Polyclonal détecte spécifiquement Selectin E/CD62e dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Cobaye, Mouton, Boeuf (Vache) et Cheval.

Aperçu rapide pour Selectin E/CD62e anticorps (N-Term) (ABIN2787940)

Antigène: Selectin E/CD62e (SELE) (Selectin E (SELE))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Mouton, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Selectin E/CD62e est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Selectin E/CD62e anticorps

Épitope: N-Term

Fonction: SELE Antibody - N-terminal region

Séquence: WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK DVGMWNDERC

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SELE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SELE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59109-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Selectin E/CD62e

Antigène: Selectin E/CD62e (SELE) (Selectin E (SELE))

Autre désignation: SELE

Sujet:

Background Information: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Gene Name: Selectin E

Alternative Symbols: ELAM, ESEL, CD62E, ELAM1, LECAM2

Protein Name: E-selectin

Poids moléculaire: 64kDa

ID gène: 6401

NCBI Accession: NP_000441

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling