RNF128 anticorps (C-Term)
Aperçu rapide pour RNF128 anticorps (C-Term) (ABIN2787946)
Antigène
Voir toutes RNF128 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- RNF128 Antibody - C-terminal region
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Séquence
- PMCKCDILKA LGIEVDVEDG SVSLQVPVSN EISNSASSHE EDNRSETASS
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Homologie
- Cow: 92%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 93%, Rat: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59127-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RNF128 (Ring Finger Protein 128 (RNF128))
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Autre désignation
- RNF128
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Sujet
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Background Information: RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.
Gene Name: Ring finger protein 128, E3 ubiquitin protein ligase
Alternative Symbols: GRAIL
Protein Name: E3 ubiquitin-protein ligase RNF128
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Poids moléculaire
- 44kDa
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ID gène
- 79589
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NCBI Accession
- NP_078815
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UniProt
- Q8TEB7
Antigène
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