TIMP2 anticorps (N-Term)

N° du produit ABIN2787967

Détail du produit anti-TIMP2 anticorps

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Cobaye, Chien, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: NADVVIRAKA VSEKEVDSGN DIYGNPIKRI QYEIKQIKMF KGPEKDIEFI

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TIMP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TIMP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 220 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: TIMP2 (TIMP2 Produits)

Synonymes: anticorps CSC-21K, anticorps DDC8, anticorps timp2l, anticorps zgc:65967, anticorps zgc:85799, anticorps D11Bwg1104e, anticorps Timp-2, anticorps TIMP-2, anticorps etID32613.12, anticorps fa96h09, anticorps timp2, anticorps wu:fa96h09, anticorps zgc:136726, anticorps TIMP metallopeptidase inhibitor 2, anticorps TIMP metallopeptidase inhibitor 2b, anticorps tissue inhibitor of metalloproteinase 2, anticorps TIMP metallopeptidase inhibitor 2a, anticorps TIMP metallopeptidase inhibitor 2 L homeolog, anticorps TIMP2, anticorps timp2b, anticorps Timp2, anticorps timp2a, anticorps timp2.L

Sujet: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Alias Symbols: CSC-21K, Metalloproteinase inhibitor 2, TIMP2, TIMP metallopeptidase inhibitor 2, Tissue inhibitor of metalloproteinases 2, Timp2
Protein Interaction Partner: BAG3, ITGA3, MMP14, ITGB1, MMP2, MMP8, SNCG, PSMA7,
Protein Size: 220

Poids moléculaire: 22 kDa

ID gène: 7077

NCBI Accession: NM_003255, NP_003246

UniProt: P16035

Pathways: cAMP Metabolic Process