RECK anticorps (Middle Region)

N° du produit ABIN2787984

Détail du produit anti-RECK anticorps

Antigène: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECK est non-conjugé

Application: Western Blotting (WB)

Séquence: SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Reck. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 971 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RECK

Antigène: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Autre désignation: Reck (RECK Produits)

Synonymes: anticorps ST15, anticorps St15, anticorps mRECK, anticorps reversion inducing cysteine rich protein with kazal motifs, anticorps reversion-inducing-cysteine-rich protein with kazal motifs, anticorps RECK, anticorps Reck

Sujet: Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971

Poids moléculaire: 104 kDa

ID gène: 53614

NCBI Accession: NM_016678, NP_057887

UniProt: Q9Z0J1