USP6 anticorps (C-Term)

N° du produit ABIN2788027

Cet anticorps anti-USP6 Polyclonal Lapin (ABIN2788027) détecte spécifiquement USP6 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Lapin et Cheval.

Aperçu rapide pour USP6 anticorps (C-Term) (ABIN2788027)

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-USP6 anticorps

Épitope: C-Term

Fonction: USP6 Antibody - C-terminal region

Séquence: NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 91%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against USP6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human USP6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59335-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur USP6

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Autre désignation: USP6

Sujet:

Background Information: USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform  2, but not isoform  3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Gene Name: ubiquitin specific peptidase 6 (Tre-2 oncogene)

Alternative Symbols: HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short

Protein Name: Ubiquitin carboxyl-terminal hydrolase 6

Poids moléculaire: 119kDa

ID gène: 9098

UniProt: P35125