USP6 anticorps (C-Term)

N° du produit ABIN2788027

Détail du produit anti-USP6 anticorps

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP6 est non-conjugé

Application: Western Blotting (WB)

Séquence: NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 91%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against USP6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human USP6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur USP6

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Autre désignation: USP6 (USP6 Produits)

Synonymes: anticorps HRP1, anticorps TRE2, anticorps TRE17, anticorps Tre-2, anticorps USP6-short, anticorps ubiquitin specific peptidase 6, anticorps ubiquitin carboxyl-terminal hydrolase 6, anticorps Ubiquitin carboxyl-terminal hydrolase 6, putative, anticorps USP6, anticorps CNG04540, anticorps ANI_1_2152104, anticorps AOR_1_208094, anticorps MCYG_00569, anticorps CC1G_15273, anticorps MGYG_01395, anticorps CGB_G0160W, anticorps LOC100282385

Sujet: USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Protein Interaction Partner: EXOSC8, CALM2, MDFI, APP, ATXN7L3, ANKRD44, RAB33B, MYL2, ARF6, RAC1, CDC42, UBC, USP32,
Protein Size: 1089

Poids moléculaire: 119 kDa

ID gène: 9098