UFD1L anticorps (Middle Region)
Aperçu rapide pour UFD1L anticorps (Middle Region) (ABIN2788062)
Antigène
Voir toutes UFD1L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- NYNEKIYELR VMETKPDKAV SIIECDMNVD FDAPLGYKEP ERQVQHEEST
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against UFD1L. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human UFD1L
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 307 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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Autre désignation
- UFD1L
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Sujet
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The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Alias Symbols: UFD1
Protein Interaction Partner: HUWE1, YOD1, VCP, UBC, SHFM1, SUZ12, BTRC, EZH2, PDCD4, NPLOC4, NFKBIA, NUB1, NEDD8, CAV1, ADRB2, FAF1, TXLNA, UNC45A, VPS33B, UBE3A, UBE2N, PSMD7, SPRTN, UBXN6, GZMK, ERLIN2, ITPR1, PPHLN1, ANAPC2, TIAM2, TAF1C, TP53, SNX1, MASP1, PIK3CA, NGFR, IGHM, F13
Protein Size: 307 -
Poids moléculaire
- 34 kDa
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ID gène
- 7353
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NCBI Accession
- NM_005659, NP_005650
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UniProt
- Q92890
Antigène
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