NUMB anticorps (C-Term)

N° du produit ABIN2788064

Détail du produit anti-NUMB anticorps

Antigène: NUMB (Numb Homolog (NUMB))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ASGNRHAEVP PGTCPVDPFE AQWAALESKS KQRTNPSPTN PFSSDLQKTF

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Numb. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 604 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NUMB

Antigène: NUMB (Numb Homolog (NUMB))

Autre désignation: Numb (NUMB Produits)

Synonymes: anticorps C14orf41, anticorps S171, anticorps c14_5527, anticorps Nb, anticorps NUMB, endocytic adaptor protein, anticorps numb homolog (Drosophila), anticorps NUMB, anticorps Numb, anticorps numb

Sujet: Numb plays a role in the process of neurogenesis. It is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. It is not required for the proliferation of neural progenitor cells before the onset of neurogenesis. It is also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. It may also mediate local repair of brain ventricular wall damage.
Alias Symbols: m-numb, mnb, m-Nb
Protein Interaction Partner: Igsf5, Eed, Grin1, Cdh2, Cdh1, Ctnnb1, Ctnna1, Lnx2, Lnx1, Notch1, Eps15, Ehd1, Ehd4,
Protein Size: 604

Poids moléculaire: 66 kDa

ID gène: 18222

NCBI Accession: NM_010949, NP_035079

Pathways: Cell-Cell Junction Organization