NUMB anticorps (Middle Region)
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- Antigène Voir toutes NUMB Anticorps
- NUMB (Numb Homolog (NUMB))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NUMB est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VGSSVAPGNT APSPSSPTSP TSDATTSLEM NNPHAIPRRH APIEQLARQG
- Homologie
- Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 83%
- Attributs du produit
- This is a rabbit polyclonal antibody against NUMB. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human NUMB
- Top Product
- Discover our top product NUMB Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NUMB (Numb Homolog (NUMB))
- Autre désignation
- NUMB (NUMB Produits)
- Synonymes
- anticorps C14orf41, anticorps S171, anticorps c14_5527, anticorps Nb, anticorps NUMB, endocytic adaptor protein, anticorps numb homolog (Drosophila), anticorps NUMB, anticorps Numb, anticorps numb
- Sujet
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The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: TP53, PRKCA, PRKCZ, PRKCE, PRKCB, UBC, SIAH1, RPL3, EGFR, NOTCH1, MDM2, APP, Trp53, Jun, EPS15, Lnx1, ITCH, GLI1, LNX2, AP2A2, PRKCH, DPYSL2, AP2A1, ITGB2, L1CAM, PRKCG, PRKCD, ITGB3, ITGB5, Eps15l1, RALBP1,
Protein Size: 592 - Poids moléculaire
- 64 kDa
- ID gène
- 8650
- Pathways
- Cell-Cell Junction Organization
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