ALDH5A1 anticorps (Middle Region)
Aperçu rapide pour ALDH5A1 anticorps (Middle Region) (ABIN2788128)
Antigène
Voir toutes ALDH5A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- AFFLEWFSEE ARRVYGDIIH TPAKDRRALV LKQPIGVAAV ITPWNFPSAM
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Homologie
- Cow: 86%, Guinea Pig: 79%, Human: 100%, Rabbit: 79%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against ALDH5A1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ALDH5A1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 535 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))
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Autre désignation
- ALDH5A1
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Sujet
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This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SSADH, SSDH
Protein Interaction Partner: MAGEA11, TOMM40, VDAC1, TIAL1, SSBP1, SOD2, EBNA-LP, ABAT,
Protein Size: 535 -
Poids moléculaire
- 57 kDa
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ID gène
- 7915
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NCBI Accession
- NM_001080, NP_001071
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UniProt
- P51649
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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