ALDH5A1 anticorps (Middle Region)

N° du produit ABIN2788128

Cet anticorps anti-ALDH5A1 Polyclonal Lapin (ABIN2788128) détecte spécifiquement ALDH5A1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Boeuf (Vache), Lapin et Cobaye.

Aperçu rapide pour ALDH5A1 anticorps (Middle Region) (ABIN2788128)

Antigène: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivité: Humain, Rat, Boeuf (Vache), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH5A1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALDH5A1 anticorps

Épitope: Middle Region

Fonction: ALDH5A1 Antibody - middle region

Séquence: AFFLEWFSEE ARRVYGDIIH TPAKDRRALV LKQPIGVAAV ITPWNFPSAM

Homologie: Cow: 86%, Guinea Pig: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ALDH5A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ALDH5A1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59587-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ALDH5A1

Antigène: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Autre désignation: ALDH5A1

Sujet:

Background Information: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Aldehyde dehydrogenase 5 family, member A1

Alternative Symbols: SSDH, SSADH

Protein Name: Succinate-semialdehyde dehydrogenase, mitochondrial

Poids moléculaire: 57kDa

ID gène: 7915

NCBI Accession: NP_001071

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process