HNMT anticorps (N-Term)

N° du produit ABIN2788140

L’anticorps Lapin Polyclonal anti-HNMT a été validé pour WB. Il convient pour détecter HNMT dans des échantillons de Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Porc et Lapin.

Aperçu rapide pour HNMT anticorps (N-Term) (ABIN2788140)

Antigène: HNMT (Histamine N-Methyltransferase (HNMT))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HNMT anticorps

Épitope: N-Term

Séquence: PGIIGRIGDT KSEIKILSIG GGAGEIDLQI LSKVQAQYPG VCINNEVVEP

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNMT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HNMT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 292 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HNMT

Antigène: HNMT (Histamine N-Methyltransferase (HNMT))

Autre désignation: HNMT

Sujet: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: HMT, HNMT-S1, HNMT-S2
Protein Interaction Partner: CAMK2D, DSP, TINF2, POT1, TERF1,
Protein Size: 292

Poids moléculaire: 33 kDa

ID gène: 3176

NCBI Accession: NM_006895, NP_008826

UniProt: P50135