SPR anticorps (C-Term)

N° du produit ABIN2788144

Cet anticorps anti-SPR Polyclonal Lapin (ABIN2788144) détecte spécifiquement SPR dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cheval et Lapin.

Aperçu rapide pour SPR anticorps (C-Term) (ABIN2788144)

Antigène: SPR (Sepiapterin Reductase (SPR))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPR anticorps

Épitope: C-Term

Fonction: SPR Antibody - C-terminal region

Séquence: ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD

Homologie: Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SPR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59628-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPR

Antigène: SPR (Sepiapterin Reductase (SPR))

Autre désignation: SPR

Sujet:

Background Information: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

Gene Name: Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Alternative Symbols: SDR38C1

Protein Name: Sepiapterin reductase

Poids moléculaire: 28kDa

ID gène: 6697

NCBI Accession: NP_003115

UniProt: P35270

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration