ARHGEF2 anticorps (C-Term)

N° du produit ABIN2788156

Détail du produit anti-ARHGEF2 anticorps

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: NTSPGVTANG EARTFNGSIE LCRADSDSSQ RDRNGNQLRS PQEEALQRLV

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ARHGEF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 986 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARHGEF2

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Autre désignation: ARHGEF2 (ARHGEF2 Produits)

Synonymes: anticorps MGC82333, anticorps MGC86214, anticorps MGC75855, anticorps AA408978, anticorps GEF, anticorps GEF-H1, anticorps GEFH1, anticorps LFP40, anticorps Lbcl1, anticorps Lfc, anticorps P40, anticorps mKIAA0651, anticorps GEF-H1/LFC, anticorps Rho/Rac guanine nucleotide exchange factor 2, anticorps Rho/Rac guanine nucleotide exchange factor 2 S homeolog, anticorps rho/rac guanine nucleotide exchange factor (GEF) 2, anticorps ARHGEF2, anticorps arhgef2.S, anticorps arhgef2, anticorps Arhgef2

Sujet: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Protein Interaction Partner: RPP25L, UBC, CEP250, RPA3, RPA2, RPA1, PPP6C, FBXO6, ANKRD28, PPP6R1, YWHAB, MMS19, PEX14, VCP, NOTCH1, YWHAZ, MARK2, RHOA, AKT1, USP21, ELAVL1, SUMO1, MARK4, YWHAH, YWHAG, MYC, MAPK1, TAF10, CGN, YWHAE, PAK1, RAC1, RRAS2, PLCG1, WASF1, YWHAQ,
Protein Size: 986

Poids moléculaire: 111 kDa

ID gène: 9181

NCBI Accession: NM_001162383, NP_001155855

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling