ALDH1A2 anticorps (N-Term)
Aperçu rapide pour ALDH1A2 anticorps (N-Term) (ABIN2788209)
Antigène
Voir toutes ALDH1A2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- ALDH1A2 Antibody - N-terminal region
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Séquence
- PVYNPATGEQ VCEVQEADKA DIDKAVQAAR LAFSLGSVWR RMDASERGRL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against ALDH1A2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH1A2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59784-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
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Autre désignation
- ALDH1A2
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Sujet
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Background Information: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
Gene Name: Aldehyde dehydrogenase 1 family, member A2
Alternative Symbols: RALDH2, RALDH2-T, RALDH(II)
Protein Name: Retinal dehydrogenase 2
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Poids moléculaire
- 57kDa
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ID gène
- 8854
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NCBI Accession
- NP_003879
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UniProt
- O94788
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Antigène
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