IGSF8 anticorps (Middle Region)

N° du produit ABIN2788247

Cet anticorps anti-IGSF8 Polyclonal Lapin (ABIN2788247) détecte spécifiquement IGSF8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Lapin, Boeuf (Vache), Porc, Chien et Cobaye.

Aperçu rapide pour IGSF8 anticorps (Middle Region) (ABIN2788247)

Antigène: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reactivité: Humain, Souris, Lapin, Boeuf (Vache), Porc, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGSF8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IGSF8 anticorps

Épitope: Middle Region

Fonction: IGSF8 Antibody - middle region

Séquence: LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 83%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%

Attributs du produit: This is a rabbit polyclonal antibody against IGSF8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IGSF8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59875-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IGSF8

Antigène: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Autre désignation: IGSF8

Sujet:

Background Information: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Gene Name: Immunoglobulin superfamily, member 8

Alternative Symbols: EWI2, PGRL, CD316, EWI-2, KCT-4, CD81P3, LIR-D1

Protein Name: Immunoglobulin superfamily member 8

Poids moléculaire: 65kDa

ID gène: 93185

NCBI Accession: NP_443100

UniProt: Q969P0