MAGE-Like 2 anticorps (N-Term)
Aperçu rapide pour MAGE-Like 2 anticorps (N-Term) (ABIN2788252)
Antigène
Voir toutes MAGE-Like 2 (MAGEL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- MAGEL2 Antibody - N-terminal region
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Séquence
- MQGLFYRPQG SSKERRTSSK ERRAPSKDRM IFAATFCAPK AVSAARAHLP
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Homologie
- Cow: 83%, Dog: 100%, Human: 100%, Pig: 88%, Rabbit: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MAGEL2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEL2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59891-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MAGE-Like 2 (MAGEL2)
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Autre désignation
- MAGEL2
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Sujet
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Background Information: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Gene Name: MAGE-like 2
Alternative Symbols: PWLS, nM15, NDNL1, SHFYNG
Protein Name: MAGE-like protein 2
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Poids moléculaire
- 58kDa
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ID gène
- 54551
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UniProt
- Q9UJ55
Antigène
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