MAGE-Like 2 anticorps (N-Term)

N° du produit ABIN2788252

Détail du produit anti-MAGE-Like 2 anticorps

Antigène: MAGE-Like 2 (MAGEL2)

Épitope: N-Term

Reactivité: Humain, Lapin, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGE-Like 2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MQGLFYRPQG SSKERRTSSK ERRAPSKDRM IFAATFCAPK AVSAARAHLP

Homologie: Cow: 83%, Dog: 100%, Human: 100%, Pig: 88%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MAGEL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 529 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAGE-Like 2

Antigène: MAGE-Like 2 (MAGEL2)

Autre désignation: MAGEL2 (MAGEL2 Produits)

Synonymes: anticorps NDNL1, anticorps nM15, anticorps MAGEL2, anticorps Mage-l2, anticorps ns7, anticorps MAGE family member L2, anticorps melanoma antigen, family L, 2, anticorps MAGEL2, anticorps Magel2

Sujet: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Alias Symbols: NDNL1, nM15
Protein Interaction Partner: VPS35, VPS26A, USP7, TRIM27, UBC,
Protein Size: 529

Poids moléculaire: 58 kDa

ID gène: 54551

NCBI Accession: NM_019066

UniProt: Q9UJ55