Rho-related GTP-binding protein anticorps (C-Term)
Aperçu rapide pour Rho-related GTP-binding protein anticorps (C-Term) (ABIN2788258)
Antigène
Voir toutes Rho-related GTP-binding protein (RhO (pan)) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Séquence
- AFFAKSAAIY NPVIYIMMNK QFRNCMLTTI CCGKNPLGDD EASATVSKTE
-
Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 93%
-
Attributs du produit
- This is a rabbit polyclonal antibody against RHO. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human RHO
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 348 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Rho-related GTP-binding protein (RhO (pan))
-
Autre désignation
- RHO
-
Classe de substances
- Chemical
-
Sujet
-
Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Alias Symbols: CSNBAD1, MGC138309, MGC138311, OPN2, RP4
Protein Interaction Partner: DERL1, EDEM1, VCP, UBC, HSPA4, DNAJB2, RHO, PPP2CA, GRK5, GRK6, ARR3, GNGT1, SAG, GRK1, PRKCA, ADRBK1,
Protein Size: 348 -
Poids moléculaire
- 39 kDa
-
ID gène
- 6010
-
NCBI Accession
- NM_000539, NP_000530
-
UniProt
- P08100
Antigène
-