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Adenosine A3 Receptor anticorps (C-Term)

ADORA3 Reactivité: Humain, Porc, Boeuf (Vache), Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2788278
  • Antigène Voir toutes Adenosine A3 Receptor (ADORA3) Anticorps
    Adenosine A3 Receptor (ADORA3)
    Épitope
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 30
    • 15
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Porc, Boeuf (Vache), Cheval, Lapin
    Hôte
    • 31
    • 1
    • 1
    Lapin
    Clonalité
    • 32
    • 1
    Polyclonal
    Conjugué
    • 25
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Adenosine A3 Receptor est non-conjugé
    Application
    • 20
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    RSCKAPKVVR KADRSRTSIL IICILITGLG IISVISHLTK RRRSQRNRRV
    Homologie
    Cow: 75%, Horse: 93%, Human: 100%, Pig: 85%, Rabbit: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against ADORA3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3
    Top Product
    Discover our top product ADORA3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 266 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Merighi, Benini, Mirandola, Gessi, Varani, Leung, Maclennan, Baraldi, Borea: "Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells." dans: Molecular pharmacology, Vol. 72, Issue 1, pp. 162-72, (2007) (PubMed).

  • Antigène
    Adenosine A3 Receptor (ADORA3)
    Autre désignation
    ADORA3 (ADORA3 Produits)
    Synonymes
    anticorps A3AR, anticorps AD026, anticorps bA552M11.5, anticorps ADORA3, anticorps 1700001D09Rik, anticorps 4930578J19Rik, anticorps A3R, anticorps AA3R, anticorps ARA3, anticorps Gpcr2, anticorps adenosine A3 receptor, anticorps adenosine receptor A3, anticorps ADORA3, anticorps Adora3, anticorps LOC100603318
    Sujet
    This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: A3AR, AD026, bA552M11.5, RP11-552M11.7
    Protein Interaction Partner: YWHAQ, YWHAZ,
    Protein Size: 266
    Poids moléculaire
    30 kDa
    ID gène
    140
    NCBI Accession
    NM_001081976, NP_001075445
    UniProt
    Q5QNY7
    Pathways
    Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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