ADRA2C anticorps (C-Term)

N° du produit ABIN2788285

Cet anticorps anti-ADRA2C est un anticorps Lapin Polyclonal détectant ADRA2C dans WB. Adapté pour Humain et Porc.

Aperçu rapide pour ADRA2C anticorps (C-Term) (ABIN2788285)

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reactivité: Humain, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADRA2C anticorps

Épitope: C-Term

Séquence: RAGAEGGAGG ADGQGAGPGA AESGALTASR EWGGERGRPL CLPPSARGCF

Homologie: Human: 100%, Pig: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ADRA2C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human ADRA2C

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADRA2C

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Autre désignation: ADRA2C

Sujet: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Alias Symbols: ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR
Protein Size: 374

Poids moléculaire: 41 kDa

ID gène: 152

NCBI Accession: NM_000683, NP_000674

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process