Factor VII anticorps (C-Term)

N° du produit ABIN2788316

Détail du produit anti-Factor VII anticorps

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Épitope: C-Term

Reactivité: Humain, Souris, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor VII est non-conjugé

Application: Western Blotting (WB)

Séquence: AAHCFDKIKN WRNLIAVLGE HDLSEHDGDE QSRRVAQVII PSTYVPGTTN

Homologie: Dog: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against F7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human F7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 466 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Factor VII

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Autre désignation: F7 (F7 Produits)

Synonymes: anticorps F7, anticorps wu:fb59f04, anticorps zgc:109870, anticorps SPCA, anticorps AI114908, anticorps ATIII, anticorps At-3, anticorps At3, anticorps LOC100223776, anticorps AI132620, anticorps Cf7, anticorps FVII, anticorps mfVII, anticorps f7, anticorps coagulation factor VII, anticorps serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1, anticorps coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog, anticorps F7, anticorps f7, anticorps Serpinc1, anticorps CpipJ_CPIJ009142, anticorps CpipJ_CPIJ010295, anticorps CpipJ_CPIJ020127, anticorps fa7, anticorps f7.S

Sujet: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.
Alias Symbols: SPCA
Protein Interaction Partner: FUS, CEP76, CEP250, VCP, RCHY1, ALB, UIMC1, USP49, DMWD, F9, F10, F7, HPN, GGCX, F3,
Protein Size: 466

Poids moléculaire: 28 kDa

ID gène: 2155

NCBI Accession: NM_000131, NP_000122

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling