Factor VII anticorps (Middle Region)

N° du produit ABIN2788317

Cet anticorps Lapin Polyclonal détecte spécifiquement Factor VII dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Boeuf (Vache), Lapin, Porc et Cheval.

Aperçu rapide pour Factor VII anticorps (Middle Region) (ABIN2788317)

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivité: Humain, Rat, Boeuf (Vache), Lapin, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor VII est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Factor VII anticorps

Épitope: Middle Region

Séquence: RCHEGYSLLA DGVSCTPTVE YPCGKIPILE KRNASKPQGR IVGGKVCPKG

Homologie: Cow: 86%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 85%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against F7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human F7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 466 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Factor VII

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Autre désignation: F7

Sujet: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.
Alias Symbols: SPCA
Protein Interaction Partner: FUS, CEP76, CEP250, VCP, RCHY1, ALB, UIMC1, USP49, DMWD, F9, F10, F7, HPN, GGCX, F3,
Protein Size: 466

Poids moléculaire: 52 kDa

ID gène: 2155

NCBI Accession: NM_000131, NP_000122

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling