CTSC anticorps (Middle Region)

N° du produit ABIN2788336

Détail du produit anti-CTSC anticorps

Antigène: CTSC (Cathepsin C (CTSC))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTSC est non-conjugé

Application: Western Blotting (WB)

Séquence: WTATTYMEYE TLTLGDMIRR SGGHSRKIPR PKPAPLTAEI QQKILHLPTS

Homologie: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CTSC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 463 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CTSC

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: CTSC (CTSC Produits)

Synonymes: anticorps CPPI, anticorps DPP-I, anticorps DPP1, anticorps DPPI, anticorps HMS, anticorps JP, anticorps JPD, anticorps PALS, anticorps PDON1, anticorps PLS, anticorps MGC69126, anticorps MGC107782, anticorps AI047818, anticorps CATC, anticorps cb912, anticorps ik:tdsubc_1h2, anticorps sb:cb146, anticorps wu:fb34g12, anticorps wu:fj58d01, anticorps cathepsin C, anticorps cathepsin C L homeolog, anticorps cathepsin CPC1, anticorps CTSC, anticorps ctsc.L, anticorps ctsc, anticorps TP03_0357, anticorps CMU_003360, anticorps CPC1, anticorps NAEGRDRAFT_80477, anticorps NAEGRDRAFT_37577, anticorps Ctsc, anticorps Smp_183330

Sujet: CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Alias Symbols: CPPI, DPP1, DPPI, HMS, JP, JPD, PALS, PLS, DPP-I
Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL,
Protein Size: 463

Poids moléculaire: 8 kDa

ID gène: 1075

NCBI Accession: NM_001814, NP_001805

UniProt: P53634