AKR1C1 anticorps (N-Term)

N° du produit ABIN2788358

Détail du produit anti-AKR1C1 anticorps

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Épitope: N-Term

Reactivité: Humain, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LERSLKNLQL DYVDLYLIHF PVSVKPGEEV IPKDENGKIL FDTVDLCATW

Homologie: Cow: 86%, Dog: 77%, Horse: 77%, Human: 100%, Pig: 77%, Rabbit: 82%, Rat: 82%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1C1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 323 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1C1

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Autre désignation: AKR1C1 (DDH Produits)

Synonymes: anticorps 2-ALPHA-HSD, anticorps 20-ALPHA-HSD, anticorps C9, anticorps DD1, anticorps DD1/DD2, anticorps DDH, anticorps DDH1, anticorps H-37, anticorps HAKRC, anticorps HBAB, anticorps MBAB, anticorps aldo-keto reductase family 1 member C1, anticorps aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase), anticorps AKR1C1

Sujet: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
Protein Interaction Partner: PTPN3, UBC, FN1, COMMD8, MAPK3, AKR1C1,
Protein Size: 323

Poids moléculaire: 36 kDa

ID gène: 1645

NCBI Accession: NM_001353, NP_001344

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process