MAPKSP1 anticorps (N-Term)

N° du produit ABIN2788404

Cet anticorps anti-MAPKSP1 Polyclonal Lapin (ABIN2788404) détecte spécifiquement MAPKSP1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour MAPKSP1 anticorps (N-Term) (ABIN2788404)

Antigène: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKSP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAPKSP1 anticorps

Épitope: N-Term

Séquence: LPSVEGLHAI VVSDRDGVPV IKVANDNAPE HALRPGFLST FALATDQGSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LAMTOR3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAMTOR3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAPKSP1

Antigène: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Autre désignation: LAMTOR3

Sujet: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
Alias Symbols: MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
Protein Interaction Partner: NIF3L1, LAMTOR2, IBTK, MBD2, BHMT, PEF1, C19orf70, MRPL43, PRR3, LPCAT1, MRPS9, MRPS35, MRPL47, TOMM22, DDX28, TSR1, RNMTL1, LAMTOR1, NDUFB11, TMCO1, MRPL39, PTRH2, RAB14, MRPL51, MRPL22, UQCRQ, PUF60, RAB31, TOMM40, MSLN, TOMM70A, NUPL1, SPCS2, PICALM, V
Protein Size: 124

Poids moléculaire: 13 kDa

ID gène: 8649

NCBI Accession: NM_021970, NP_068805

UniProt: Q9UHA4

Pathways: Signalisation PI3K-Akt