MRPL45 anticorps (C-Term)

N° du produit ABIN2788460

Détail du produit anti-MRPL45 anticorps

Antigène: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPL45 est non-conjugé

Application: Western Blotting (WB)

Séquence: YGSWRMHTKI VPPWAPPKQP ILKTVMIPGP QLKPEEEYEE AQGEAQKPQL

Homologie: Cow: 75%, Human: 100%, Mouse: 91%, Rat: 82%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against MRPL45. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MRPL45

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 306 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MRPL45 (ABIN2788460)

Kotani, Akabane, Takeyasu, Ueda, Takeuchi: "Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes." dans: Nucleic acids research, Vol. 41, Issue 6, pp. 3713-22, (2013) (PubMed).

Détails sur MRPL45

Antigène: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Autre désignation: MRPL45 (MRPL45 Produits)

Synonymes: anticorps L45mt, anticorps MRP-L45, anticorps 2600005P05Rik, anticorps AU043542, anticorps R75241, anticorps mrlp45, anticorps mitochondrial ribosomal protein L45, anticorps mitochondrial ribosomal protein L45 L homeolog, anticorps Mrpl45, anticorps MRPL45, anticorps mrpl45.L

Sujet: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
Alias Symbols: MGC11321, L45mt, MRP-L45
Protein Interaction Partner: TRIM23, UBC, C1QBP, TMEM177, MRPL24, MARCKSL1, MRPL9, MRPL11, MRPL32, MRPL38, MRPL47, SYNJ2BP, MRPL50, MRPL51, MRPL37, MRPL15, MRPL13, ZC3H4, HNRNPR, MRPL19, SDHB, ILF3, CUL3, ICT1, KBTBD7, G3BP1,
Protein Size: 306

Poids moléculaire: 35 kDa

ID gène: 84311

NCBI Accession: NM_032351, NP_115727

UniProt: Q9BRJ2