TCHP anticorps (C-Term)

N° du produit ABIN2788476

Il existe 1 publication pour ce produit. L’anticorps anti-TCHP Polyclonal Lapin est utilisé pour la détection de TCHP dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour TCHP anticorps (C-Term) (ABIN2788476)

Antigène: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCHP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TCHP anticorps

Épitope: C-Term

Fonction: TCHP Antibody - C-terminal region

Séquence: IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against TCHP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TCHP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60515-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TCHP (ABIN2788476)

Wong, Vaz, Lee, Zhao, Luo, Archer, Preiss, Tanavde, Vardy: "Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).

Détails sur TCHP

Antigène: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Autre désignation: TCHP

Sujet:

Background Information: TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.

Gene Name: Trichoplein, keratin filament binding

Alternative Symbols: TpMs

Protein Name: Trichoplein keratin filament-binding protein

Poids moléculaire: 61kDa

ID gène: 84260

NCBI Accession: NP_115676

UniProt: Q9BT92