SPANXB1 anticorps (Middle Region)

N° du produit ABIN2788571

Détail du produit anti-SPANXB1 anticorps

Antigène: SPANXB1 (SPANX Family, Member B1 (SPANXB1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPANXB1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MPETPTGDSD PQPAPKKMKT SESSTILVVR YRRNVKRTSP EELVNDHARE

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SPANXB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human SPANXB1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPANXB1

Antigène: SPANXB1 (SPANX Family, Member B1 (SPANXB1))

Autre désignation: SPANXB1 (SPANXB1 Produits)

Synonymes: anticorps B1, anticorps CT11.2, anticorps SPANX-B, anticorps SPANXB, anticorps SPANX family member B1, anticorps SPANXB1

Sujet: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis.
Alias Symbols: B1, CT11.2, SPANX-B, SPANXB
Protein Interaction Partner: SUMO2,
Protein Size: 103

Poids moléculaire: 12 kDa

ID gène: 728695

NCBI Accession: NM_032461, NP_115850

UniProt: Q9NS25