AKR1D1 anticorps (Middle Region)

N° du produit ABIN2788589

Détail du produit anti-AKR1D1 anticorps

Antigène: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1D1 est non-conjugé

Application: Western Blotting (WB)

Séquence: YVDLYIIEVP MAFKPGDEIY PRDENGKWLY HKSNLCATWE AMEACKDAGL

Homologie: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 100%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1D1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AKR1D1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 326 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1D1

Antigène: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Autre désignation: AKR1D1 (AKR1D1 Produits)

Synonymes: anticorps 3o5bred, anticorps CBAS2, anticorps SRD5B1, anticorps 3-oxo-5-beta-steroid 4-dehydrogenase-like, anticorps aldo-keto reductase family 1 member D1, anticorps aldo-keto reductase family 1, member D1, anticorps aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase), anticorps LOC491379, anticorps AKR1D1, anticorps Akr1d1

Sujet: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Alias Symbols: 3o5bred, CBAS2, SRD5B1
Protein Size: 326

Poids moléculaire: 37 kDa

ID gène: 6718

NCBI Accession: NM_005989, NP_005980

UniProt: P51857

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process