AKR1D1 anticorps (Middle Region)

N° du produit ABIN2788589

Cet anticorps Lapin Polyclonal détecte spécifiquement AKR1D1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval et Porc.

Aperçu rapide pour AKR1D1 anticorps (Middle Region) (ABIN2788589)

Antigène: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1D1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AKR1D1 anticorps

Épitope: Middle Region

Fonction: AKR1D1 Antibody - middle region

Séquence: YVDLYIIEVP MAFKPGDEIY PRDENGKWLY HKSNLCATWE AMEACKDAGL

Homologie: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 100%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1D1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AKR1D1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60804-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1D1

Antigène: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Autre désignation: AKR1D1

Sujet:

Background Information: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

Gene Name: Aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

Alternative Symbols: CBAS2, SRD5B1, 3o5bred

Protein Name: 3-oxo-5-beta-steroid 4-dehydrogenase

Poids moléculaire: 37kDa

ID gène: 6718

NCBI Accession: NP_005980

UniProt: P51857

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process