CYP7B1 anticorps (C-Term)

N° du produit ABIN2788601

Cet anticorps Lapin Polyclonal détecte spécifiquement CYP7B1 dans WB. Il présente une réactivité avec des échantillons de Humain, Boeuf (Vache), Rat, Porc, Lapin, Chien et Cheval.

Aperçu rapide pour CYP7B1 anticorps (C-Term) (ABIN2788601)

Antigène: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Reactivité: Humain, Boeuf (Vache), Rat, Porc, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP7B1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CYP7B1 anticorps

Épitope: C-Term

Séquence: AMYYLLRHPE AMAAVRDEID RLLQSTGQKK GSGFPIHLTR EQLDSLICLE

Homologie: Cow: 85%, Dog: 93%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CYP7B1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP7B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 506 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP7B1

Antigène: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Autre désignation: CYP7B1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Alias Symbols: CBAS3, CP7B, SPG5A
Protein Interaction Partner: UBC,
Protein Size: 506

Poids moléculaire: 58 kDa

ID gène: 9420

NCBI Accession: NM_004820, NP_004811

UniProt: O75881

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Intracellular Steroid Hormone Receptor Signaling