Calpain 3 anticorps (C-Term)
Aperçu rapide pour Calpain 3 anticorps (C-Term) (ABIN2788627)
Antigène
Voir toutes Calpain 3 (CAPN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DRANSNKELG VDQESEEGKG KTSPDKQKQS PQPQPGSSDQ ESEEQQQFRN
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Homologie
- Cow: 79%, Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 85%, Sheep: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against CAPN3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 815 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Calpain 3 (CAPN3)
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Autre désignation
- CAPN3
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Sujet
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Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Alias Symbols: CANP3, CANPL3, LGMD2, LGMD2A, MGC10767, MGC11121, MGC14344, MGC4403, nCL-1, p94
Protein Interaction Partner: WDYHV1, OSGIN1, NECAB2, DYSF, TTN, YWHAQ, CAPN3, FLNC,
Protein Size: 815 -
Poids moléculaire
- 93 kDa
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ID gène
- 825
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NCBI Accession
- NM_024344, NP_077320
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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