Calpain 3 anticorps (Middle Region)

N° du produit ABIN2788628

Détail du produit anti-Calpain 3 anticorps

Antigène: Calpain 3 (CAPN3)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain 3 est non-conjugé

Application: Western Blotting (WB)

Séquence: SPQPQPGSSD QESEEQQQFR NIFKQIAGDD MEICADELKK VLNTVVNKHK

Homologie: Cow: 75%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%, Sheep: 75%

Attributs du produit: This is a rabbit polyclonal antibody against CAPN3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 309 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Calpain 3

Antigène: Calpain 3 (CAPN3)

Autre désignation: CAPN3 (CAPN3 Produits)

Synonymes: anticorps capn3, anticorps MGC80925, anticorps zgc:92687, anticorps CAPN3, anticorps AI323605, anticorps Capa-3, anticorps Capa3, anticorps Lp82, anticorps p94, anticorps Lp84, anticorps Lp85, anticorps CANP3, anticorps CANPL3, anticorps LGMD2, anticorps LGMD2A, anticorps nCL-1, anticorps SKM-CALP, anticorps SKM-CALPOV, anticorps nCL1, anticorps calpain 1, (mu/I) large subunit L homeolog, anticorps calpain 3a, (p94), anticorps calpain 3, anticorps capn1.L, anticorps capn3a, anticorps CAPN3, anticorps Capn3

Sujet: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Alias Symbols: CANP3, CANPL3, LGMD2, LGMD2A, MGC10767, MGC11121, MGC14344, MGC4403, nCL-1, p94
Protein Interaction Partner: WDYHV1, OSGIN1, NECAB2, DYSF, TTN, YWHAQ, CAPN3, FLNC,
Protein Size: 309

Poids moléculaire: 35 kDa

ID gène: 825

NCBI Accession: NM_173088, NP_775111

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development