Cathepsin K anticorps (Middle Region)

N° du produit ABIN2788629

Cet anticorps anti-Cathepsin K Polyclonal Lapin (ABIN2788629) détecte spécifiquement Cathepsin K dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio) et Chévre.

Aperçu rapide pour Cathepsin K anticorps (Middle Region) (ABIN2788629)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cathepsin K anticorps

Épitope: Middle Region

Fonction: CTSK Antibody - middle region

Séquence: SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY

Homologie: Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CTSK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CTSK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60949-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: CTSK

Sujet:

Background Information: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Gene Name: Cathepsin K

Alternative Symbols: CTSO, PKND, PYCD, CTS02, CTSO1, CTSO2

Protein Name: Cathepsin K

Poids moléculaire: 37kDa

ID gène: 1513

NCBI Accession: NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades