Cathepsin K anticorps (Middle Region)

N° du produit ABIN2788629

Détail du produit anti-Cathepsin K anticorps

Antigène: Cathepsin K (CTSK)

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB)

Séquence: SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY

Homologie: Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CTSK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CTSK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 329 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: CTSK (CTSK Produits)

Synonymes: anticorps CTS02, anticorps CTSO, anticorps CTSO1, anticorps CTSO2, anticorps PKND, anticorps PYCD, anticorps AI323530, anticorps MMS10-Q, anticorps Ms10q, anticorps catK, anticorps CTSK, anticorps wu:fa95f03, anticorps wu:fb08b05, anticorps zgc:110367, anticorps cts02, anticorps ctso, anticorps ctso1, anticorps ctso2, anticorps pknd, anticorps pycd, anticorps OC-2, anticorps catk, anticorps cathepsin K, anticorps cathepsin K L homeolog, anticorps Cathepsin K, anticorps CTSK, anticorps Ctsk, anticorps ctsk, anticorps ctsk.L, anticorps catk

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Protein Interaction Partner: LIG4, SERPINB13, SERPINB3, KNG1, SPARC, FGFR3,
Protein Size: 329

Poids moléculaire: 37 kDa

ID gène: 1513

NCBI Accession: NM_000396, NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades