Histone Cluster 2, H4a (HIST2H4A) (Middle Region) anticorps

N° du produit ABIN2788644

Détail du produit

Antigène: Histone Cluster 2, H4a (HIST2H4A)

Épitope: Middle Region

Reactivité: Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Séquence: LARRGGVKRI SGLIYEETRG VLKVFLENVI RDAVTYTEHA KRKTVTAMDV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Hist2h4. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 103 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Histone Cluster 2, H4a (HIST2H4A)

Autre désignation: Hist2h4 (HIST2H4A Produits)

Synonymes: anticorps FO108, anticorps H4, anticorps H4/n, anticorps H4F2, anticorps H4FN, anticorps HIST2H4, anticorps X04652, anticorps Hist4h4, anticorps histone cluster 2 H4 family member a, anticorps histone cluster 2, H4, anticorps histone H4, anticorps HIST2H4A, anticorps Hist2h4, anticorps HIST2H4

Sujet: Hist2h4 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H4, X04652
Protein Interaction Partner: Csrp2bp, Wdtc1, Myocd, Zbtb16, Tcf3,
Protein Size: 103

Poids moléculaire: 11 kDa

ID gène: 97122

NCBI Accession: NM_033596, NP_291074

UniProt: P62806

Pathways: Telomere Maintenance