Histone Cluster 2, H4a (HIST2H4A) (Middle Region) anticorps

N° du produit ABIN2788644

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone Cluster 2, H4a dans WB. Il présente une réactivité avec des échantillons de Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour Histone Cluster 2, H4a (HIST2H4A) (Middle Region) anticorps (ABIN2788644)

Antigène: Histone Cluster 2, H4a (HIST2H4A)

Reactivité: Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: Middle Region

Fonction: Hist2h4 Antibody - middle region

Séquence: LARRGGVKRI SGLIYEETRG VLKVFLENVI RDAVTYTEHA KRKTVTAMDV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Hist2h4. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60985-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Histone Cluster 2, H4a (HIST2H4A)

Autre désignation: Hist2h4

Sujet:

Background Information: Hist2h4 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Name: Histone cluster 2, H4

Alternative Symbols: H4, H4c1, H4c2, H4c3, H4c4, H4c6, H4c8, H4c9, H4c11, H4c12, H4f16, Hist2, X04652, Hist2h4

Protein Name: Histone H4

Poids moléculaire: 11kDa

ID gène: 97122

NCBI Accession: NP_291074

UniProt: P62806

Pathways: Telomere Maintenance